Toxic reaction to local anesthetics
article written by anesthet.
Toxic reaction to local anesthetics can be simplified or broken down into two categories. Those that are of a stimulatory nature and those that are of a depressive phase.
- Stimulatory phase:
- Nervousness
- Restlessness
- Talkativeness
- Coreiform movements
- Tremors or twitching
- Clonic convulsions
Depessive phase:
- Hypotention
- Bradycardia, followed by tachycardia
- Shock
- Loss of consciousness
- Respiratory depression
The use of certain illicit compounds can trigger signs of both phases. In our world of changing “life styles” unfortunately clinicians are at the fore front of facing these toxic signs. As an example, the use of anabolic steroids.
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